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TMFHelical (98.74)

Academic drugs

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September 18, 2007 – Comments (0)

One item that gets a lot of press and inadvertently gives the public the impression that the drug industry is dragging its collective feet is academic PR.  I see a lot of biotech news services, and occasionally the general press, picking up on some recently published academic research where the latest CURE to x y or z has been discovered.  These are typically in model systems and generally don't go much further.

 So, to use this blog to link another, Derek Lowe has written a couple of recent commentaries on this subject. See:

http://pipeline.corante.com/archives/2007/09/12/drugs_from_where.php

http://pipeline.corante.com/archives/2007/09/18/ugly_but_useful.php

Among other items (he's real good, and everyone in my industry should be reading him), he points out that the finds in academia seldom make for promising drug candidates for a variety of reasons.  How a compound will behave in the body and it promiscuity being the primary issues.  He gives an example of just such a compound in the second post.

But..as he also points out, these non-drug compounds can be wonderful research tools that go a long way to advancing our knowedge about targets, disease states, etc.  We are fortunate IMO that the government has always seen fit to fund a good deal of purely academic research.  While it may not show us the next great drug, it will almost certainly help light the way.

Zz

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