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portefeuille (99.66)

fund trades

Recs

4

December 26, 2011 – Comments (250)

What this "fund" is about is described here and here.

trades in spreadsheet.

 

largest long positions (USD).

EMC, 2117510.00.
DSCO, 2003800.00.
VOW:GY, 578986.55.
AAPL, 379130.20.
SQNM, 291384.00.
SVNT, 263350.00.
XDAX:GY, 251345.42.
ATPG, 247365.00.
MDAXEX:GY, 243392.41.
ALGETA:NO, 235274.40.

 

short positions (USD).

SPY, 9795225.00.
VMW, 460185.00.
IWM, 447300.00.

 

largest gains (USD).

VMW, 256436.00.
ANTH, 212829.00.
FOLD, 186690.20.
MNTA, 156591.50.
VOW:GY, 141529.71.
ANDS, 104939.00.
EXEL, 86180.70.
AAPL, 69532.45.
IBB, 63988.00.
EXAS, 60433.00.

 

largest losses (USD).

DSCO, 759375.78.
SPY, 592083.00.
SVNT, 121184.00.
CBK:GY, 117559.02.
MRNA, 87638.46.
TKMR, 78046.94.
ATPG, 65018.00.
ECX:GY, 52896.24.
HGSI, 43589.20.
ALGETA:NO, 39080.21.

 

preceding posts.

March 06, 2010
March 10, 2010
March 13, 2010
March 30, 2010
April 02, 2010
April 08, 2010
April 17, 2010
April 26, 2010
May 22, 2010
June 17, 2010
July 21, 2010
August 03, 2010
August 11, 2010
August 26, 2010
September 04, 2010
September 18, 2010
October 06, 2010
October 16, 2010
October 24, 2010
October 28, 2010
November 03, 2010
November 12, 2010
November 24, 2010
December 11, 2010
December 17, 2010
December 24, 2010
December 27, 2010
December 31, 2010
January 12, 2011
February 01, 2011
February 10, 2011
February 22, 2011
March 07, 2011
March 24, 2011
April 01, 2011
April 14, 2011
April 27, 2011
May 06, 2011
May 12, 2011
May 20, 2011
May 31, 2011
June 18, 2011
June 30, 2011
July 21, 2011
July 29, 2011
August 05, 2011
August 08, 2011
August 10, 2011
August 11, 2011
August 15, 2011
August 18, 2011
August 25, 2011
August 30, 2011
September 03, 2011
September 08, 2011
September 14, 2011
September 16, 2011
September 22, 2011
September 27, 2011
October 05, 2011

October 09, 2011
October 23, 2011
October 30, 2011
November 09, 2011
November 22, 2011
December 11, 2011

250 Comments – Post Your Own

#1) On December 26, 2011 at 6:34 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - December 26, 2011) with/without DSCO: -15.2%/+7.1%.

cash: -$1.29 million.

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#2) On December 26, 2011 at 7:26 AM, portefeuille (99.66) wrote:

buy 3500 ALGETA:NO, limit 170.00 NOK.

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#3) On December 26, 2011 at 11:30 AM, rofgile (99.41) wrote:

Perhaps disco is coming back into style this spring?

 -Rof 

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#4) On December 26, 2011 at 11:58 AM, Valyooo (99.47) wrote:

You should make a chart with relative performance to SPY...

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#5) On December 27, 2011 at 8:05 AM, portefeuille (99.66) wrote:

A Push to Tie New Drugs to Testing

currently 11100 QGEN shares in the fund with break-even of around 16.46 USD.

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#6) On December 27, 2011 at 8:45 AM, portefeuille (99.66) wrote:

buy 195 ALXN, limit 75.00 USD.

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#7) On December 27, 2011 at 8:51 AM, portefeuille (99.66) wrote:

bought 3500 ALGETA:NO 26.28 USD (156.50 NOK / 5.9553 NOK/USD).

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#8) On December 27, 2011 at 9:24 AM, portefeuille (99.66) wrote:

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential

Synthetic Molecules Trigger MMP-Targeting mAbs to Treat IBD

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#9) On December 27, 2011 at 9:33 AM, portefeuille (99.66) wrote:

sell 300 ATPG, limit 7.70 USD.

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#10) On December 27, 2011 at 9:42 AM, portefeuille (99.66) wrote:

bought 195 ALXN 69.24 USD,
sold 300 ATPG 7.70 USD.

currently 450/34200 ALXN/ATPG shares in the fund with break-even of around 56.31/9.07 USD.

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#11) On December 27, 2011 at 9:44 AM, portefeuille (99.66) wrote:

sell 8000 PBTH, limit 4.47 USD.

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#12) On December 27, 2011 at 9:49 AM, portefeuille (99.66) wrote:

sell 3000 DSCO, limit 1.78 USD.

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#13) On December 27, 2011 at 9:51 AM, portefeuille (99.66) wrote:

sold 3000 DSCO 1.79 USD.

currently 1162000 DSCO shares in the fund with break-even of around 2.37 USD.

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#14) On December 27, 2011 at 9:56 AM, portefeuille (99.66) wrote:

buy 32000 EMC, limit 22.00 USD.

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#15) On December 27, 2011 at 10:03 AM, portefeuille (99.66) wrote:

sold 1700 RIGL 8.03 USD,
bought 32000 EMC 21.80 USD.

currently 129000/3300 EMC/RIGL shares in the fund with break-even of around 21.71/6.08 USD.

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#16) On December 27, 2011 at 10:18 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - December 27, 2011) with/without DSCO: -13.8%/+6.1%.

cash: -$2.07 million.

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#17) On December 27, 2011 at 10:28 AM, portefeuille (99.66) wrote:

buy 15000 KARO:SS, limit 1.70 SEK.

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#18) On December 27, 2011 at 10:35 AM, portefeuille (99.66) wrote:

Karo Bio Enters Collaboration with Pfizer to Discover and Develop Innovative Drugs for Autoimmune Diseases

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#19) On December 27, 2011 at 10:48 AM, portefeuille (99.66) wrote:

bought 15000 KARO:SS 0.2038 USD (1.40 SEK / 6.8688 SEK/USD).

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#20) On December 27, 2011 at 11:01 AM, portefeuille (99.66) wrote:

The Genomics in Medicine Lecture Series

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#21) On December 27, 2011 at 11:31 AM, portefeuille (99.66) wrote:

sell 14000 EXEL, limit 4.90 USD.

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#22) On December 27, 2011 at 11:35 AM, portefeuille (99.66) wrote:

sold 14000 EXEL 4.92 USD.

currently 30000 EXEL shares in the fund with break-even of around 1.64 USD.

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#23) On December 27, 2011 at 11:49 AM, portefeuille (99.66) wrote:

sell 150 ALXN, limit 72.00 USD.

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#24) On December 27, 2011 at 12:15 PM, portefeuille (99.66) wrote:

sell 2100 ZIOP, limit 4.30 USD.

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#25) On December 27, 2011 at 12:16 PM, portefeuille (99.66) wrote:

sold 2100 ZIOP 4.32 USD.

currently 15000 ZIOP shares in the fund with break-even of around 3.81 USD.

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#26) On December 27, 2011 at 12:30 PM, portefeuille (99.66) wrote:

Therapeutic siRNA silencing in inflammatory monocytes in mice

Novel technique uses RNA interference to block inflammation

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#27) On December 27, 2011 at 12:35 PM, portefeuille (99.66) wrote:

https://twitter.com/portefeuillefun

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#28) On December 27, 2011 at 12:45 PM, portefeuille (99.66) wrote:

sold 150 ALXN 72.00 USD.

currently 300 ALXN shares in the fund with break-even of around 48.47 USD.

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#29) On December 27, 2011 at 1:06 PM, portefeuille (99.66) wrote:

sell 120 MDVN 46.60 USD.

currently 500 MDVN shares in the fund with break-even of around -8.26 USD.

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#30) On December 27, 2011 at 1:08 PM, portefeuille (99.66) wrote:

sell 120 MDVN 46.60 USD.

sold 120 MDVN 46.60 USD.

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#31) On December 27, 2011 at 1:12 PM, portefeuille (99.66) wrote:

sell 3500 EXEL, limit 4.97 USD.

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#32) On December 27, 2011 at 1:31 PM, portefeuille (99.66) wrote:

sold 3500 EXEL 4.97 USD.

currently 26500 EXEL shares in the fund with break-even of around 1.20 USD.

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#33) On December 27, 2011 at 1:44 PM, portefeuille (99.66) wrote:

buy 1800 NTAP, limit 36.70 USD.

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#34) On December 27, 2011 at 1:45 PM, portefeuille (99.66) wrote:

bought 1800 NTAP 36.61 USD.

currently 4500 NTAP shares in the fund with break-even of around 36.22 USD.

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#35) On December 27, 2011 at 2:05 PM, portefeuille (99.66) wrote:

sell 1000 CHTP, limit 5.20 USD.

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#36) On December 27, 2011 at 2:06 PM, portefeuille (99.66) wrote:

sold 1000 CHTP 5.24 USD.

currently 3000 CHTP shares in the fund with break-even of around -2.95 USD.

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#37) On December 27, 2011 at 2:24 PM, portefeuille (99.66) wrote:

buy 125 SA, limit 18.00 USD.

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#38) On December 27, 2011 at 2:25 PM, portefeuille (99.66) wrote:

bought 125 SA 16.75 USD.

currently 200 SA shares in the fund with break-even of around -44.11 USD.

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#39) On December 27, 2011 at 2:37 PM, portefeuille (99.66) wrote:

sell 500 NSPH, limit 1.40 USD.

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#40) On December 27, 2011 at 2:39 PM, portefeuille (99.66) wrote:

sold 500 NSPH 1.57 USD.

currently 1500 NSPH shares in the fund with break-even of around 1.90 USD.

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#41) On December 27, 2011 at 2:44 PM, portefeuille (99.66) wrote:

sell 2500 EXEL, limit 5.07 USD.

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#42) On December 27, 2011 at 2:45 PM, portefeuille (99.66) wrote:

sold 2500 EXEL 5.09 USD.

currently 24000 EXEL shares in the fund with break-even of around 0.79 USD.

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#43) On December 27, 2011 at 3:11 PM, portefeuille (99.66) wrote:

sell 300 RIGL, limit 8.18 USD.

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#44) On December 27, 2011 at 3:13 PM, portefeuille (99.66) wrote:

sold 300 RIGL 8.19 USD.

currently 3000 RIGL shares in the fund with break-even of around 5.87 USD.

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#45) On December 27, 2011 at 3:35 PM, portefeuille (99.66) wrote:

sell 300 ACHN, limit 7.90 USD.

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#46) On December 27, 2011 at 3:37 PM, portefeuille (99.66) wrote:

sold 300 ACHN, limit 7.97 USD.

currently 2300 ACHN shares in the fund with break-even of around 3.17 USD.

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#47) On December 27, 2011 at 6:16 PM, portefeuille (99.66) wrote:

buy 120 VRUS, limit 124.00 USD.

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#48) On December 27, 2011 at 6:46 PM, portefeuille (99.66) wrote:

Health Care the Sector of the Year?



enlarge

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#49) On December 28, 2011 at 6:28 AM, portefeuille (99.66) wrote:

sell 5000 KARO:SS, limit 1.63 SEK.

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#50) On December 28, 2011 at 7:03 AM, portefeuille (99.66) wrote:

sell 300 XRTX, limit 14.48 USD.

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#51) On December 28, 2011 at 7:36 AM, portefeuille (99.66) wrote:

Online gaming surges on US revival hopes

currently 2500 BPTY:LN shares in the fund with break-even of around 161.93 p.

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#52) On December 28, 2011 at 7:47 AM, portefeuille (99.66) wrote:

sell 1400 BPTY:LN, limit 178.00 p.

 

The online poker gold rush

Ruling increases odds for online gambling legalization

Internet decision helps rally some gaming stocks

Antigua Optimistic On US Gaming Opinion

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#53) On December 28, 2011 at 8:12 AM, portefeuille (99.66) wrote:

Obama Administration’s Support During 2011 for Biotech Yields Mixed Results

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#54) On December 28, 2011 at 9:36 AM, portefeuille (99.66) wrote:

sell 3500 OPTR, limit 11.96 USD.

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#55) On December 28, 2011 at 9:46 AM, portefeuille (99.66) wrote:

bought 120 VRUS 123.62 USD,
sold 3500 OPTR 11.98 USD.

currently 2000/650 OPTR/VRUS shares in the fund with break-even of around 4.25/70.17 USD.

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#56) On December 28, 2011 at 9:48 AM, portefeuille (99.66) wrote:

buy 4000 EXEL, limit 4.82 USD.

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#57) On December 28, 2011 at 9:50 AM, portefeuille (99.66) wrote:

bought 4000 EXEL 4.80 USD.

currently 28000 EXEL shares in the fund with break-even of around 1.36 USD.

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#58) On December 28, 2011 at 10:09 AM, portefeuille (99.66) wrote:

buy 700 GDXJ, limit 23.70 USD.

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#59) On December 28, 2011 at 10:12 AM, portefeuille (99.66) wrote:

bought 700 GDXJ 23.69 USD.

currently 1500 GDXJ shares in the fund with break-even of around 27.94 USD.

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#60) On December 28, 2011 at 10:19 AM, portefeuille (99.66) wrote:

buy 4000 EXEL, limit 4.82 USD.

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#61) On December 28, 2011 at 10:20 AM, portefeuille (99.66) wrote:

bought 4000 EXEL 4.75 USD.

currently 32000 EXEL shares in the fund with break-even of around 1.79 USD.

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#62) On December 28, 2011 at 10:24 AM, portefeuille (99.66) wrote:

buy 300 ATPG, limit 7.20 USD.

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#63) On December 28, 2011 at 10:26 AM, portefeuille (99.66) wrote:

bought 300 ATPG 7.16 USD.

currently 34500 ATPG shares in the fund with break-even of around 9.05 USD.

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#64) On December 28, 2011 at 11:16 AM, portefeuille (99.66) wrote:

Biogen CEO: New Year Is 'Remarkable Time' For Biotech

currently 270 BIIB shares in the fund with break-even of around 71.89 USD.

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#65) On December 28, 2011 at 11:40 AM, portefeuille (99.66) wrote:

sell 12000 CRME, limit 2.26 USD.

change that to

sell 7000 CRME, limit 2.21 USD.

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#66) On December 28, 2011 at 12:08 PM, portefeuille (99.66) wrote:

buy 160 CREE, limit 22.00 USD.

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#67) On December 28, 2011 at 12:09 PM, portefeuille (99.66) wrote:

bought 160 CREE 21.41 USD.

currently 500 CREE shares in the fund with break-even of around 28.84 USD.

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#68) On December 28, 2011 at 1:23 PM, portefeuille (99.66) wrote:

performance (March 8, 2010 - December 28, 2011) with/without DSCO: -17.6%/+3.0%.

cash: -$2.04 million.

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#69) On December 28, 2011 at 1:44 PM, portefeuille (99.66) wrote:

Tough Markets: Punishing Hedge Funds Since 2003

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#70) On December 28, 2011 at 1:49 PM, portefeuille (99.66) wrote:

sell 200 XBI, limit 65.50 USD.

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#71) On December 28, 2011 at 1:52 PM, portefeuille (99.66) wrote:

sold 200 XBI 65.85 USD.

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#72) On December 28, 2011 at 4:09 PM, portefeuille (99.66) wrote:

sold 7000 CRME 2.21 USD.

sell 5000 CRME, limit 2.26 USD in extended or regular trading.

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#73) On December 28, 2011 at 4:18 PM, portefeuille (99.66) wrote:

sold 5000 CRME 2.27 USD.

currently 33000 CRME shares in the fund with break-even of around 1.33 USD.

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#74) On December 28, 2011 at 4:36 PM, portefeuille (99.66) wrote:

Year in Review: Melanoma Drug Still on a Roll

currently 460 ROG:VX shares in the fund with break-even of around 147.78 USD.

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#75) On December 29, 2011 at 6:52 AM, portefeuille (99.66) wrote:

All eyes on German renewable energy efforts

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#76) On December 29, 2011 at 8:21 AM, portefeuille (99.66) wrote:

 

 

currently 7000 SGMO shares in the fund with break-even of around 5.04 USD.

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#77) On December 29, 2011 at 8:26 AM, portefeuille (99.66) wrote:

sell 8000 PBTH, limit 4.47 USD.

change that to

sell 5000 PBTH, limit 4.22 USD.

 

buy 4500 ANTH, limit 6.30 USD.

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#78) On December 29, 2011 at 8:41 AM, portefeuille (99.66) wrote:

buy 9000 FOLD, limit 3.28 USD in extended or regular trading.

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#79) On December 29, 2011 at 9:20 AM, portefeuille (99.66) wrote:

CHTP - Cardiovascular and Renal Drugs Advisory Committee meeting - February 23, 2012

http://www.ofr.gov/OFRUpload/OFRData/2011-33561_PI.pdf

currently 3000 CHTP shares in the fund with break-even of around -2.95 USD.

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#80) On December 29, 2011 at 9:25 AM, portefeuille (99.66) wrote:

Peregrine Provides Update on HCV Clinical Program

sell 6000 PPHM, limit 1.16 USD in extended or regular trading.

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#81) On December 29, 2011 at 9:31 AM, portefeuille (99.66) wrote:

sell 6000 PPHM, limit 1.16 USD in extended or regular trading.

change that to

sell 4000 PPHM, limit 1.11 USD.

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#82) On December 29, 2011 at 9:32 AM, portefeuille (99.66) wrote:

sell 5000 CRME, limit 2.46 USD.

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#83) On December 29, 2011 at 9:35 AM, portefeuille (99.66) wrote:

sell 5000 CRME, limit 2.46 USD.

change that to

sell 3000 CRME, limit 2.42 USD.

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#84) On December 29, 2011 at 9:36 AM, portefeuille (99.66) wrote:

sold 3000 CRME 2.44 USD.

currently 30000 CRME shares in the fund with break-even of around 1.22 USD.

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#85) On December 29, 2011 at 9:47 AM, portefeuille (99.66) wrote:

bought 4500 ANTH 5.83 USD,
bought 9000 FOLD 3.18 USD.

currently 8000/66000 ANTH/FOLD shares in the fund with break-even of around -20.67/+0.46 USD.

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#86) On December 29, 2011 at 10:24 AM, portefeuille (99.66) wrote:

sell 4000 ANTH, limit 6.04 USD.

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#87) On December 29, 2011 at 11:29 AM, portefeuille (99.66) wrote:

sell 4000 PPHM, limit 1.11 USD.

change that to

sell 3000 PPHM, limit 1.04 USD.

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#88) On December 29, 2011 at 11:35 AM, portefeuille (99.66) wrote:

sold 4000 ANTH 6.04 USD,
sold 3000 PPHM 1.04 USD.

currently 4000/34000 ANTH/PPHM shares in the fund with break-even of around -47.39/+0.94 USD.

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#89) On December 29, 2011 at 11:38 AM, portefeuille (99.66) wrote:

sell 400 AMRN, limit 6.92 USD.

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#90) On December 29, 2011 at 11:39 AM, portefeuille (99.66) wrote:

sold 400 AMRN 6.93 USD.

currently 6600 AMRN shares in the fund with break-even of around 8.42 USD.

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#91) On December 29, 2011 at 2:27 PM, portefeuille (99.66) wrote:

#76

Method of the Year 2011

Transcription Activator-Like Effector Nuclease

TAL effector nucleases collection

Precision gene targeting in stem cells corrects disease-causing mutations

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#92) On December 29, 2011 at 3:53 PM, portefeuille (99.66) wrote:

sold 7000 CRME 2.62 USD.

(the "caps" game blog post comments were not working. posted via twitter. https://twitter.com/portefeuillefun)

currently 23000 CRME shares in the fund with break-even of around 0.79 USD.

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#93) On December 29, 2011 at 3:55 PM, portefeuille (99.66) wrote:

buy 1500 BDSI, limit 0.85 USD.

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#94) On December 29, 2011 at 4:02 PM, portefeuille (99.66) wrote:

bought 1500 BDSI 0.84 USD.

currently 4300 BDSI shares in the fund with break-even of around 3.74 USD.

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#95) On December 29, 2011 at 4:15 PM, portefeuille (99.66) wrote:

bought 1500 BDSI 0.84 USD.

currently 4300 BDSI shares in the fund with break-even of around 3.74 USD.

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#96) On December 30, 2011 at 7:17 AM, portefeuille (99.66) wrote:

Bioshares Investor Report: Benitec – Building Proof of Concept Data in Four Diseases (pdf)

Van Leeuwenhoeck Institute Report - BENITEC
Silencing is golden (pdf)

currently 50000 BLT:AU shares in the fund with break-even of around 0.0378 AUD.

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#97) On December 30, 2011 at 7:21 AM, portefeuille (99.66) wrote:

buy 600 MSB:AU, limit 8.00 AUD.

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#98) On December 30, 2011 at 8:09 AM, portefeuille (99.66) wrote:

sell 30 PRC:FP, limit 52.80 EUR.

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#99) On December 30, 2011 at 8:49 AM, portefeuille (99.66) wrote:

sell 3000 CRME, limit 2.88 USD in extended or regular trading,
sell 150 RHT, limit 41.95 USD.

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#100) On December 30, 2011 at 8:59 AM, portefeuille (99.66) wrote:

sold PRC:FP 68.37 USD (52.80 EUR * 1.2949 USD/EUR).

currently 40 PRC:FP shares in the fund with break-even of around 4.10 EUR.

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#101) On December 30, 2011 at 9:33 AM, portefeuille (99.66) wrote:

sell 1700 IBB, limit 103.20 USD.

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#102) On December 30, 2011 at 9:43 AM, portefeuille (99.66) wrote:

sold 1700 IBB 103.92 USD.

currently 0 IBB shares in the fund. gain of around 64719.00 USD.

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#103) On December 30, 2011 at 10:05 AM, portefeuille (99.66) wrote:

sold 5000 PBTH 4.22 USD.

currently 41000 PBTH shares in the fund with break-even of around 3.45 USD.

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#104) On December 30, 2011 at 10:20 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - December 30, 2011) with/without DSCO: -17.2%/+6.5%.

cash: -$1.80 million.

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#105) On December 30, 2011 at 11:21 AM, portefeuille (99.66) wrote:

sell 7000 FOLD, limit 3.42 USD.

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#106) On December 30, 2011 at 11:23 AM, portefeuille (99.66) wrote:

sold 7000 FOLD 3.43 USD.

currently 59000 FOLD shares in the fund with break-even of around 0.11 USD.

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#107) On December 30, 2011 at 12:03 PM, portefeuille (99.66) wrote:

sell 3500 ANTH, limit 6.25 USD.

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#108) On December 30, 2011 at 12:05 PM, portefeuille (99.66) wrote:

sold 3500 ANTH 6.25 USD.

currently 500 ANTH shares in the fund with break-even of around -422.84 USD.

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#109) On December 30, 2011 at 12:12 PM, portefeuille (99.66) wrote:

sell 3900 ALNY, limit 8.30 USD.

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#110) On December 30, 2011 at 12:14 PM, portefeuille (99.66) wrote:

sold 3900 ALNY 8.34 USD.

currently 13000 ALNY shares in the fund with break-even of around 9.68 USD.

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#111) On December 30, 2011 at 12:49 PM, portefeuille (99.66) wrote:

buy 270 AMZN, limit 174.00 USD.

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#112) On December 30, 2011 at 12:50 PM, portefeuille (99.66) wrote:

bought 270 AMZN 173.59 USD.

currently 600 AMZN shares in the fund with break-even of around 132.62 USD.

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#113) On December 30, 2011 at 2:07 PM, portefeuille (99.66) wrote:

sell 200 ALNY, limit 6.80 USD.

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#114) On December 30, 2011 at 3:43 PM, portefeuille (99.66) wrote:

buy 550 CBRX, limit 2.55 USD.

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#115) On December 30, 2011 at 3:44 PM, portefeuille (99.66) wrote:

bought 550 CBRX 2.51 USD.

currently 2000 CBRX shares in the fund with break-even of around 0.76 USD.

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#116) On December 30, 2011 at 3:50 PM, portefeuille (99.66) wrote:

sold 200 ALNY 8.32 USD.

currently 12800 ALNY shares in the fund with break-even of around 9.70 USD.

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#117) On December 30, 2011 at 5:13 PM, portefeuille (99.66) wrote:

buy 410 ECH, limit 60.00 USD,
buy 800 RIGL, limit 8.20 USD.

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#118) On December 30, 2011 at 5:34 PM, portefeuille (99.66) wrote:

sold 14400 SQNM 4.39 USD.

currently 54000 SQNM shares in the fund with break-even of around 4.47 USD.

 

sell 300 INHX, limit 11.98 USD
sell 290 VRUS, limit 132.00 USD
sell 900 MNTA, limit 18.18 USD
sell 5000 KARO:SS, limit 1.63 SEK
sell 300 XRTX, limit 14.48 USD
sell 1400 BPTY:LN, limit 178.00 p
sell 3000 CRME, limit 2.88 USD in extended or regular trading
sell 150 RHT, limit 41.95 USD

cancel these orders.

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#119) On December 30, 2011 at 5:48 PM, portefeuille (99.66) wrote:

performance (March 8, 2010 - December 30, 2011) with/without DSCO: -16.4%/+7.3%.

cash: -$1.70 million.

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#120) On December 30, 2011 at 5:59 PM, portefeuille (99.66) wrote:

sell 70 VRUS, limit 127.90 USD in extended or regular trading.

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#121) On December 30, 2011 at 6:02 PM, portefeuille (99.66) wrote:

sold 70 VRUS 127.90 USD.

currently 580 VRUS shares in the fund with break-even of around 63.21 USD.

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#122) On January 01, 2012 at 5:11 AM, portefeuille (99.66) wrote:

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#123) On January 01, 2012 at 5:35 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 1, 2012) with/without DSCO: -16.5%/+7.2%.

cash: -$1.69 million.

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#124) On January 01, 2012 at 6:05 AM, portefeuille (99.66) wrote:

largest long positions (USD).

EMC, 2778660.00.
DSCO, 1952160.00.
VOW:GY, 575168.66.
AAPL, 380700.00.
ALGETA:NO, 319960.52.
SVNT, 256450.00.
ATPG, 253920.00.
XDAX:GY, 249730.79.
MDAXEX:GY, 243605.19.
SQNM, 240300.00.

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#125) On January 01, 2012 at 3:49 PM, portefeuille (99.66) wrote:

buy 200 GDXJ, limit 54.00 USD,
sell 600 GDXJ, limit 24.50 USD,
sell 120 GILD, limit 39.00 USD,
sell 40 GOOG, limit 540.00 USD,
buy 700 HGSI, limit 8.00 USD,
sell 50 IBM, limit 187.00 USD.

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#126) On January 01, 2012 at 3:50 PM, portefeuille (99.66) wrote:

buy 200 GDXJ, limit 54.00 USD

buy 200 GDX, limit 54.00 USD

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#127) On January 01, 2012 at 4:04 PM, portefeuille (99.66) wrote:

Porsche expects 2012 to be another record year

currently 2675 PAH3:GY shares in the fund with break-even of around 26.47 EUR.

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#128) On January 01, 2012 at 4:09 PM, portefeuille (99.66) wrote:

Porsche preferred shares in Frankfurt trading.



enlarge

 



enlarge

 



enlarge

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#129) On January 02, 2012 at 10:58 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 2, 2012) with/without DSCO: -15.0%/+8.7%.

cash: -$1.69 million.

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#130) On January 02, 2012 at 11:06 AM, portefeuille (99.66) wrote:

Roche scientist provides a look at drugmaker's early pipeline

currently 1325 ROG:VX shares in the fund with break-even of around 147.28 CHF.

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#131) On January 02, 2012 at 11:34 AM, portefeuille (99.66) wrote:

Teva Announces Management Succession

currently 250 TEVA shares in the fund with break-even of around 52.02 USD.



enlarge

 



enlarge

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#132) On January 02, 2012 at 5:34 PM, portefeuille (99.66) wrote:

Available Pharma Products list (pdf)

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#133) On January 03, 2012 at 6:18 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 3, 2012) with/without DSCO: -13.3%/+10.4%.

cash: -$1.69 million.

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#134) On January 03, 2012 at 6:22 AM, portefeuille (99.66) wrote:

AVEO and Astellas Announce Tivozanib Successfully Demonstrated Progression-Free Survival Superiority over Sorafenib in Patients with Advanced Renal Cell Cancer in Phase 3 TIVO-1 Trial

currently 200 AVEO shares in the fund with break-even of around 17.28 USD.

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#135) On January 03, 2012 at 6:40 AM, portefeuille (99.66) wrote:

Amarin Commences 2012 With Letter to Shareholders

currently 6600 AMRN shares in the fund with break-even of around 8.42 USD.

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#136) On January 03, 2012 at 8:09 AM, portefeuille (99.66) wrote:

Δ12-prostaglandin J3, an omega-3 fatty acid–derived metabolite, selectively ablates leukemia stem cells in mice

Fish oil compound stops leukemia in mice

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#137) On January 03, 2012 at 8:36 AM, portefeuille (99.66) wrote:

buy 250 AVEO, limit 16.90 USD in extended or regular trading.

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#138) On January 03, 2012 at 8:38 AM, portefeuille (99.66) wrote:

bought 250 AVEO 16.90 USD.

currently 450 AVEO shares in the fund with break-even of around 17.07 USD.

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#139) On January 03, 2012 at 8:48 AM, portefeuille (99.66) wrote:

Why Placebos Work Wonders

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#140) On January 03, 2012 at 8:50 AM, portefeuille (99.66) wrote:

buy 600 AVEO, limit 16.20 USD in extended or regular trading.

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#141) On January 03, 2012 at 8:52 AM, portefeuille (99.66) wrote:

bought 600 AVEO 16.10 USD.

currently 1050 AVEO shares in the fund with break-even of around 16.52 USD.

Report this comment
#142) On January 03, 2012 at 9:02 AM, portefeuille (99.66) wrote:

buy 250 AVEO, limit 15.85 USD in extended or regular trading.

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#143) On January 03, 2012 at 9:06 AM, portefeuille (99.66) wrote:

bought 250 AVEO 15.85 USD.

currently 1300 AVEO shares in the fund with break-even of around 16.39 USD.

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#144) On January 03, 2012 at 9:13 AM, portefeuille (99.66) wrote:

sell 700 AVEO, limit 16.28 USD in extended or regular trading.

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#145) On January 03, 2012 at 9:26 AM, portefeuille (99.66) wrote:

sold 700 AVEO 16.28 USD.

currently 600 AVEO shares in the fund with break-even of around 16.51 USD.

sell 200 AVEO, limit 16.98 USD in extended or regular trading.

Report this comment
#146) On January 03, 2012 at 9:30 AM, portefeuille (99.66) wrote:

sold 200 AVEO 16.98 USD.

currently 400 AVEO shares in the fund with break-even of around 16.28 USD.

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#147) On January 03, 2012 at 9:33 AM, portefeuille (99.66) wrote:

sell 1500 BDSI, limit 0.98 USD.

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#148) On January 03, 2012 at 9:56 AM, portefeuille (99.66) wrote:

sold 4000 FOLD 3.48 USD,
sold 600 ISIS 7.18 USD,
sold 2500 ITMN 12.88 USD,
bought 600 MSB:AU 7.07 USD (6.90 AUD * 1.024 USD/AUD),
bought 410 ECH 58.31 USD,
bought 800 RIGL 8.07 USD,
bought 200 GDX 52.79 USD,
sold 600 GDXJ 25.52 USD,
sold 120 GILD 41.46 USD,
sold 40 GOOG 652.94 USD,
bought 700 HGSI 7.53 USD,
sold 50 IBM 187.00 USD.

Report this comment
#149) On January 03, 2012 at 9:56 AM, portefeuille (99.66) wrote:

buy 700 AVEO, limit 16.00 USD.

Report this comment
#150) On January 03, 2012 at 9:59 AM, portefeuille (99.66) wrote:

bought 700 AVEO 15.26 USD.

currently 1100 AVEO shares in the fund with break-even of around 15.63 USD.

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#151) On January 03, 2012 at 10:10 AM, portefeuille (99.66) wrote:

sold 30 VPHM 28.40 USD.

sell 3000 PBTH, limit 4.68 USD.

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#152) On January 03, 2012 at 11:43 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 3, 2012) with/without DSCO: -11.8%/+11.2%.

cash: -$1.65 million.

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#153) On January 03, 2012 at 11:57 AM, portefeuille (99.66) wrote:

sell 800 ALNY, limit 8.65 USD.

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#154) On January 03, 2012 at 12:01 PM, portefeuille (99.66) wrote:

sold 800 ALNY 8.66 USD.

currently 12000 ALNY shares in the fund with break-even of around 9.77 USD.

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#155) On January 03, 2012 at 12:31 PM, portefeuille (99.66) wrote:

http://beta.fool.com/portefeuille/

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#156) On January 03, 2012 at 1:55 PM, portefeuille (99.66) wrote:

buy 400 AVEO, limit 14.00 USD.

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#157) On January 03, 2012 at 1:56 PM, portefeuille (99.66) wrote:

bought 400 AVEO 13.98 USD.

currently 1500 AVEO shares in the fund with break-even of around 15.19 USD.

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#158) On January 03, 2012 at 2:13 PM, portefeuille (99.66) wrote:

sell 1500 ALXA, limit 0.92 USD.

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#159) On January 03, 2012 at 2:14 PM, portefeuille (99.66) wrote:

sold 1500 ALXA 0.9249 USD.

currently 3000 ALXA shares in the fund with break-even of around 1.52 USD.

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#160) On January 03, 2012 at 2:28 PM, portefeuille (99.66) wrote:

sell 200 XRTX, limit 14.00 USD.

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#161) On January 03, 2012 at 2:30 PM, portefeuille (99.66) wrote:

sold 200 XRTX 14.02 USD.

currently 500 XRTX shares in the fund with break-even of around 7.22 USD.

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#162) On January 03, 2012 at 7:34 PM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 4, 2012) with/without DSCO: -10.2%/+12.5%.

cash: -$1.65 million.

Report this comment
#163) On January 03, 2012 at 8:28 PM, portefeuille (99.66) wrote:

sell 250 VRUS, limit 131.70 USD.

Report this comment
#164) On January 04, 2012 at 5:37 AM, portefeuille (99.66) wrote:

sell 70000 DSCO, limit 2.34 USD
sell 4000 EWI, limit 14.15 USD
sell 35000 SVNT, limit 2.88 USD
sell 15000 DSCO, limit 2.07 USD
sell 500 IRWD, limit 12.48 USD
sell 1500 ALXA, limit 1.40 USD in extended or regular trading
sell 1000 YMI, limit 2.58 USD in extended or regular trading
sell 500 ISTA, limit 8.45 USD
sell 300 INHX, limit 11.98 USD
sell 1500 BDSI, limit 0.98 USD
sell 3000 PBTH, limit 4.68 USD

cancel these orders.

Report this comment
#165) On January 04, 2012 at 5:41 AM, portefeuille (99.66) wrote:

sell 300 INHX, limit 11.98 USD

forget that.

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#166) On January 04, 2012 at 5:55 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 4, 2012) with/without DSCO: -10.5%/+12.1%.

cash: -$1.65 million.

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#167) On January 04, 2012 at 6:12 AM, portefeuille (99.66) wrote:

Scientists say unreported drug data a health hazard

Amsterdam Molecular Therapeutics Receives US Orphan Designation for Hemophilia B Gene Therapy

buy 14000 AMT:NA, limit 0.60 EUR.

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#168) On January 04, 2012 at 6:24 AM, portefeuille (99.66) wrote:

#167 a few links to related info from here and here.

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B (pdf)

Gene therapy proves effective for hemophilia B

Treatment for Blood Disease Is Gene Therapy Landmark

Merry Christmas for Patients with Hemophilia B

 

also see this post.

gene therapy

Report this comment
#169) On January 04, 2012 at 6:26 AM, portefeuille (99.66) wrote:

Alnylam Reports Positive Preliminary Clinical Results for ALN-PCS, an RNAi Therapeutic Targeting PCSK9 for the Treatment of Severe Hypercholesterolemia

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#170) On January 04, 2012 at 6:43 AM, portefeuille (99.66) wrote:

bought 14000 AMT:NA 0.53 USD (0.405 EUR * 1.3012 USD/EUR).

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#171) On January 04, 2012 at 7:25 AM, portefeuille (99.66) wrote:

ALNY-PCS-PhI-PrelimResutls-Jan2012 - presentation (pdf)

Conference Call to Discuss Preliminary Phase I Results of ALN-PCS Clinical Trial - 1/04/12 8:30 a.m.

currently 12000/1650/16800/5600/470000/67000 ALNY/ARWR/ISIS/MRNAD/SLN:LN/TKMR shares in the fund with break-even of around 9.77/7.82/8.31/16.70/1.97/2.78 USD/USD/USD/USD/p/USD.

also see these posts.

TKMR

ALNY

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#172) On January 04, 2012 at 7:37 AM, portefeuille (99.66) wrote:

#167

Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study (pdf)

BMJ: Discipline Researchers Who Withhold Research Results

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#173) On January 04, 2012 at 7:39 AM, portefeuille (99.66) wrote:

#167,172 Medicine's Biggest Threat

Report this comment
#174) On January 04, 2012 at 7:48 AM, portefeuille (99.66) wrote:

buy 200 CLVS, limit 15.00 USD.

Report this comment
#175) On January 04, 2012 at 9:08 AM, portefeuille (99.66) wrote:

http://www.alnylam.com/capella/

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#176) On January 04, 2012 at 9:24 AM, portefeuille (99.66) wrote:

Arrowhead Announces FDA Clearance to Initiate AdipotideTM Phase I Clinical Trial

currently 1650 ARWR shares in the fund with break-even of around 7.82 USD.

 

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#177) On January 04, 2012 at 9:32 AM, portefeuille (99.66) wrote:

Vestas Future Questioned After Forecasts Cut Twice Since October

currently 500 VWS:DC shares in the fund with break-even of around 235.55 DKK.

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#178) On January 04, 2012 at 9:33 AM, portefeuille (99.66) wrote:

sell 15000 FOLD, limit 3.60 USD.

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#179) On January 04, 2012 at 9:39 AM, portefeuille (99.66) wrote:

bought 200 CLVS 14.13 USD,
sold 15000 FOLD 3.61 USD.

currently 200/40000 CLVS/FOLD shares in the fund with break-even of around 14.13/-1.54 USD.

Report this comment
#180) On January 04, 2012 at 9:59 AM, portefeuille (99.66) wrote:

buy 500 INHX, limit 9.00 USD.

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#181) On January 04, 2012 at 10:00 AM, portefeuille (99.66) wrote:

bought 500 INHX 8.68 USD.

currently 7500 INHX shares in the fund with break-even of around 3.21 USD.

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#182) On January 04, 2012 at 10:13 AM, portefeuille (99.66) wrote:

sell 500 INHX, limit 9.00 USD.

Report this comment
#183) On January 04, 2012 at 10:14 AM, portefeuille (99.66) wrote:

sold 500 INHX 9.27 USD.

currently 7000 INHX shares in the fund with break-even of around 2.78 USD.

Report this comment
#184) On January 04, 2012 at 10:33 AM, portefeuille (99.66) wrote:

sell 50 REGN, limit 57.50 USD.

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#185) On January 04, 2012 at 10:37 AM, portefeuille (99.66) wrote:

sold 50 REGN 57.59 USD.

currently 220 REGN shares in the fund with break-even of around 30.81 USD.

Report this comment
#186) On January 04, 2012 at 10:40 AM, portefeuille (99.66) wrote:

sell 400 AVEO, limit 14.20 USD.

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#187) On January 04, 2012 at 10:49 AM, portefeuille (99.66) wrote:

sell 100 ARIA, limit 12.70 USD.

Report this comment
#188) On January 04, 2012 at 10:51 AM, portefeuille (99.66) wrote:

sold 100 ARIA 12.76 USD.

currently 300 ARIA shares in the fund with break-even of around -67.33 USD.

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#189) On January 04, 2012 at 10:54 AM, portefeuille (99.66) wrote:

sell 500 ITMN, limit 13.05 USD.

Report this comment
#190) On January 04, 2012 at 10:56 AM, portefeuille (99.66) wrote:

sold 500 ITMN 13.06 USD.

currently 11500 ITMN shares in the fund with break-even of around 7.60 USD.

Report this comment
#191) On January 04, 2012 at 11:01 AM, portefeuille (99.66) wrote:

sold 400 AVEO 14.20 USD.

currently 1100 AVEO shares in the fund with break-even of around 15.55 USD.

Report this comment
#192) On January 04, 2012 at 11:12 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 4, 2012) with/without DSCO: -12.2%/+10.2%.

cash: -$1.58 million.

Report this comment
#193) On January 04, 2012 at 11:26 AM, portefeuille (99.66) wrote:

sell 150 BMRN, limit 35.00 USD.

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#194) On January 04, 2012 at 11:27 AM, portefeuille (99.66) wrote:

sold 150 BMRN 35.20 USD.

currently 350 BMRN shares in the fund with break-even of around 16.20 USD.

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#195) On January 04, 2012 at 11:39 AM, portefeuille (99.66) wrote:

Stealth tactics of bacteria revealed

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

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#196) On January 04, 2012 at 11:40 AM, portefeuille (99.66) wrote:

sell 1500 ITMN, limit 13.55 USD.

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#197) On January 04, 2012 at 11:42 AM, portefeuille (99.66) wrote:

sold 1500 ITMN 13.57 USD.

currently 10000 ITMN shares in the fund with break-even of around 6.71 USD.

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#198) On January 04, 2012 at 12:02 PM, portefeuille (99.66) wrote:

#167,172

What Data? Alice In Clinical Trial Wonderland

Missing clinical trial data

Missing Data: The Elephant That’s Not in the Room

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#199) On January 04, 2012 at 12:08 PM, portefeuille (99.66) wrote:

sell 12000 DSCO, limit 1.79 USD.

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#200) On January 04, 2012 at 12:11 PM, portefeuille (99.66) wrote:

sold 12000 DSCO 1.79 USD.

currently 1150000 DSCO shares in the fund with break-even of around 2.38 USD.

Report this comment
#201) On January 04, 2012 at 1:35 PM, portefeuille (99.66) wrote:

sell 60000 DSCO, limit 1.81 USD.

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#202) On January 04, 2012 at 1:36 PM, portefeuille (99.66) wrote:

sold 60000 DSCO 1.81 USD.

currently 1090000 DSCO shares in the fund with break-even of around 2.41 USD.

Report this comment
#203) On January 04, 2012 at 1:44 PM, portefeuille (99.66) wrote:

sell 400 GNOM, limit 3.40 USD.

Report this comment
#204) On January 04, 2012 at 1:45 PM, portefeuille (99.66) wrote:

sold 400 GNOM 3.42 USD.

currently 600 GNOM shares in the fund with break-even of around 6.67 USD.

Report this comment
#205) On January 04, 2012 at 2:02 PM, portefeuille (99.66) wrote:

buy 28000 EXEL, limit 4.55 USD.

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#206) On January 04, 2012 at 2:04 PM, portefeuille (99.66) wrote:

bought 28000 EXEL 4.52 USD.

currently 60000 EXEL shares in the fund with break-even of around 3.06 USD.

sell 20000 EXEL, limit 4.58 USD.

Report this comment
#207) On January 04, 2012 at 2:10 PM, portefeuille (99.66) wrote:

sell 3000 SIGA, limit 2.99 USD.

Report this comment
#208) On January 04, 2012 at 2:34 PM, portefeuille (99.66) wrote:

ALN-PCS02 Results Provide Glimpse of First RNAi Therapeutics Blockbuster

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#209) On January 04, 2012 at 2:38 PM, portefeuille (99.66) wrote:

buy 5000 SQNM, limit 4.30 USD.

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#210) On January 04, 2012 at 2:40 PM, portefeuille (99.66) wrote:

bought 5000 SQNM 4.29 USD.

currently 59000 SQNM shares in the fund with break-even of around 4.46 USD.

Report this comment
#211) On January 04, 2012 at 2:59 PM, portefeuille (99.66) wrote:

UniCredit Slumps After Announcing 43% Discount on Share Sale

currently 650 UCG:MI shares in the fund with break-even of around 22.43 EUR.

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#212) On January 04, 2012 at 3:57 PM, portefeuille (99.66) wrote:

sell 600 QGEN, limit 14.50 USD.

Report this comment
#213) On January 04, 2012 at 3:58 PM, portefeuille (99.66) wrote:

sold 600 QGEN 14.50 USD.

currently 10500 QGEN shares in the fund with break-even of around 16.57 USD.

Report this comment
#214) On January 04, 2012 at 6:40 PM, portefeuille (99.66) wrote:

F.D.A. Restricts Use of Antibiotics in Livestock

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#215) On January 04, 2012 at 7:50 PM, portefeuille (99.66) wrote:

buy (to cover) 17500 SPY, limit 127.68 USD in extended or regular trading.

Report this comment
#216) On January 04, 2012 at 7:52 PM, portefeuille (99.66) wrote:

bought (to cover) 17500 SPY 127.68 USD.

currently -60000 SPY shares in the fund with break-even of around 116.15 USD.

Report this comment
#217) On January 04, 2012 at 7:53 PM, portefeuille (99.66) wrote:

bought (to cover) 17500 SPY 127.68 USD.

bought (to cover) 17500 SPY 127.67 USD.

Report this comment
#218) On January 04, 2012 at 8:01 PM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 5, 2012) with/without DSCO: -9.5%/+10.0%.

cash: -$3.80 million.

Report this comment
#219) On January 04, 2012 at 8:11 PM, portefeuille (99.66) wrote:

sell 240 AAPL, limit 406.00 USD,
sell 10000 DSCO, limit 1.76 USD,
sell 8000 EMC, limit 21.83 USD,
sell 5000 SVNT, limit 2.38 USD,
sell short (to open) 1000 VMW, limit 82.00 USD,
sell 800 VOW:GY, limit 107.00 EUR.

Report this comment
#220) On January 04, 2012 at 8:25 PM, portefeuille (99.66) wrote:

sell 100 AAPL, limit 350.00 USD,
sell 20000 DSCO, limit 1.60 USD,
sell 7000 EMC, limit 20.00 USD,
sell 5000 SVNT, limit 2.10 USD,
sell short (to open) 1000 VMW, limit 75.00 USD,
sell 1200 VOW:GY, limit 95.00 EUR.

Report this comment
#221) On January 05, 2012 at 8:41 AM, portefeuille (99.66) wrote:

buy (to cover) 3000 SPY, limit 127.50 USD in extended or regular trading.

Report this comment
#222) On January 05, 2012 at 8:43 AM, portefeuille (99.66) wrote:

bought (to cover) 3000 SPY 127.45 USD.

currently -57000 SPY shares in the fund with break-even of around 115.55 USD.

Report this comment
#223) On January 05, 2012 at 8:51 AM, portefeuille (99.66) wrote:

sold 2000 VOW:GY 140.96 USD (109.00 EUR * 1.2932 USD/EUR).

currently 2200 VOW:GY shares in the fund with break-even of around 55.13 EUR.

Report this comment
#224) On January 05, 2012 at 8:57 AM, portefeuille (99.66) wrote:

sell 100 AAPL, limit 350.00 USD

change that to

sell 120 AAPL, limit 414.70 USD in extended or regular trading.

Report this comment
#225) On January 05, 2012 at 9:05 AM, portefeuille (99.66) wrote:

sold 120 AAPL 414.90 USD.

currently 820 AAPL shares in the fund with break-even of around 316.84 USD.

Report this comment
#226) On January 05, 2012 at 9:15 AM, portefeuille (99.66) wrote:

sell 1000 TRGT, limit 5.90 USD in extended or regular trading.

Report this comment
#227) On January 05, 2012 at 9:17 AM, portefeuille (99.66) wrote:

sold 1000 TRGT 5.95 USD.

currently 7700 TRGT shares in the fund with break-even of around 7.70 USD.

Report this comment
#228) On January 05, 2012 at 9:21 AM, portefeuille (99.66) wrote:

sell 2000 QQQ, limit 57.00 USD in extended or regular trading.

Report this comment
#229) On January 05, 2012 at 9:24 AM, portefeuille (99.66) wrote:

sold 2000 QQQ 57.01 USD.

currently no QQQ shares in the fund. gain of around 1386.20 USD.

buy (to cover) 2000 SPY, limit 127.20 USD in extended or regular trading.

Report this comment
#230) On January 05, 2012 at 9:28 AM, portefeuille (99.66) wrote:

bought (to cover) 2000 SPY 127.09 USD.

currently -55000 SPY shares in the fund with break-even of around 115.13 USD.

Report this comment
#231) On January 05, 2012 at 9:31 AM, portefeuille (99.66) wrote:

sell 600 DNDN, limit 9.30 USD.

Report this comment
#232) On January 05, 2012 at 9:42 AM, portefeuille (99.66) wrote:

sold 240 AAPL 414.95 USD,
sold 30000 DSCO 1.77 USD,
sold 7000 EMC 21.67 USD,
sold 8000 EMC 21.83 USD,
sold 5000 SVNT 2.34 USD,
sold short (to open) 1000 VMW 81.76 USD,
sold short (to open) 1000 VMW 82.00 USD,
sold 600 DNDN 9.30 USD.

Report this comment
#233) On January 05, 2012 at 9:50 AM, portefeuille (99.66) wrote:

sell 11000 PBTH, limit 5.08 USD.

Report this comment
#234) On January 05, 2012 at 9:51 AM, portefeuille (99.66) wrote:

sold 11000 PBTH, limit 5.09 USD.

currently 30000 PBTH shares in the fund with break-even of around 2.85 USD.

Report this comment
#235) On January 05, 2012 at 10:00 AM, portefeuille (99.66) wrote:

buy (to cover) 2000 SPY, limit 127.00 USD.

Report this comment
#236) On January 05, 2012 at 10:01 AM, portefeuille (99.66) wrote:

bought (to cover) 2000 SPY 126.67 USD.

sell 10000 EMC, limit 21.70 USD.

Report this comment
#237) On January 05, 2012 at 10:04 AM, portefeuille (99.66) wrote:

sold 10000 EMC 21.75 USD.

Report this comment
#238) On January 05, 2012 at 10:22 AM, portefeuille (99.66) wrote:

sold 5000 SVNT 2.38 USD.

currently 105000 SVNT shares in the fund with break-even of around 3.44 USD.

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#239) On January 05, 2012 at 10:54 AM, portefeuille (99.66) wrote:

sold 20000 EXEL 4.58 USD.

currently 40000 EXEL shares in the fund with break-even of around 2.30 USD.

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#240) On January 05, 2012 at 11:09 AM, portefeuille (99.66) wrote:

performance (March 8, 2010 - January 5, 2012) with/without DSCO: -10.6%/+10.0%.

cash: -$3.20 million.

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#241) On January 05, 2012 at 11:14 AM, portefeuille (99.66) wrote:

sell 1500 ITMN, limit 14.03 USD.

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#242) On January 05, 2012 at 11:17 AM, portefeuille (99.66) wrote:

sold 1500 ITMN 14.03 USD.

currently 8500 ITMN shares in the fund with break-even of around 5.42 USD.

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#243) On January 05, 2012 at 11:19 AM, portefeuille (99.66) wrote:

sell short (to open) 2000 SPY, limit 127.18 USD in extended or regular trading.

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#244) On January 05, 2012 at 11:26 AM, portefeuille (99.66) wrote:

Hepatitis C vaccine: Oxford researchers' trial 'promising'

Experimental hepatitis C vaccine shows early promise

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#245) On January 05, 2012 at 11:29 AM, portefeuille (99.66) wrote:

sold short (to open) 2000 SPY 127.18 USD.

currently -55000 SPY shares in the fund with break-even of around 115.15 USD.

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#246) On January 05, 2012 at 11:37 AM, portefeuille (99.66) wrote:

sell 100 ACOM, limit 26.60 USD.

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#247) On January 05, 2012 at 11:40 AM, portefeuille (99.66) wrote:

sold 100 ACOM 26.61 USD.

currently 50 ACOM shares in the fund with break-even of around -11.76 USD.

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#248) On January 05, 2012 at 12:19 PM, portefeuille (99.66) wrote:

sell 2800 ISIS, limit 7.40 USD.

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#249) On January 05, 2012 at 12:23 PM, portefeuille (99.66) wrote:

sold 2800 ISIS 7.42 USD.

currently 14000 ISIS shares in the fund with break-even of around 8.49 USD.

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#250) On January 05, 2012 at 12:27 PM, portefeuille (99.66) wrote:

continued here.

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