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JaysRage (94.10)

Pharmaceuticals

Recs

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November 04, 2009 – Comments (8)

As an investor, I tend to take a Buffet approach to investing in most situations.   If I can't fully understand the industry that a stock is involved in, why pricing and valuation make sense and where that stock will be in the next year or so, I usually stay hands off.   I have never invested in a pharmaceutical company and I might never do it, but I admit, it is an interesting industry, mostly because it is SO different from everything else. 

For the most part, I'm at a complete loss when it comes to pharmaceuticals, but I have been watching from a distance for a while to learn how it works.    I have the following impressions about pharmaceutical stocks.   For those who buy a lot in this sector, please feel free to comment on these observations. 

I don't focus on large cap stocks, so my observations are purely in the small cap space. 

1)  There are many more failing drug companies than successful ones. 

2)  One drug can make or break the stock price of the entire company.

3)  The most successful companies have multiple drugs in the pipeline, even after they have one successful drug that has gone to market.

4)  Competition is fierce, and the success of one drug company often means the failure of several others who were competing to be the first to get a drug to market in a certain sector. 

How does one work their way through this sector?   Do you make multiple small plays on different companies working on a drug in the same area, knowing that a success means a 10X increase that would offset the losses by the others?    What is the magic formula?     

8 Comments – Post Your Own

#1) On November 04, 2009 at 12:36 PM, leohaas (93.93) wrote:

Jay, you are not taking the Buffett approach. WB only invests in companies he understands well. Considering the questions you ask in the final paragraph, your understanding of the sector and individual companies in the sector is cursory at best.

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#2) On November 04, 2009 at 12:52 PM, vriguy (80.51) wrote:

Trying to guess which whether a drug in the pipeline will be a blockbuster is futile in the early stages, and is chancy at best even in the late stages - even for those with lots of background knowledge.  I'd say bet on the big boys - their pipelines usually have multiple promising drugs, they have the cash to buy out a small player with a better drug, and the marketing muscle and knowhow to exploit any opportunity.  Spread it around, or go with a sector mutual fund/ETF with a good track record.  I have small positions in BMY, GSK, NVS, AZN, PFE that I plan to hold through the coming decade or longer, and to which I add on the dips.

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#3) On November 04, 2009 at 12:54 PM, cdulan (89.10) wrote:

Jay, I work in the Pharma industry but not as a scientist.

I think you are being prudent in not investing there based on your comfort level.  I have been working in Pharma for three years and trying to learn how to invest there the whole time.  All I can say is that it is as precarious as you mention.

Even companies like Genentech or Biogen base a tremendous amount of their sales on just a few drugs.

 I think the best approach is to focus on big Pharma, where the participants have the most diversified income streams and buy for dividend yields.  Pharma is having a huge problem replacing growth once drugs go off patent but as a return on investment, big drugs are holding up better against generics than widely thought.

Good luck.

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#4) On November 04, 2009 at 4:18 PM, JaysRage (94.10) wrote:

I appreciate all the comments and insights.  vriguy/cdulan, thanks for your insights.   They are appreciated.      

leohass -- I think you misunderstood me.   I have never invested in pharmaceuticals and right now, I don't even have any inclination to do so.    However, I love to learn about different investing strategies (much in the same way that I study different generals in history and how they approached a battlefield or a war), and from all that I've seen, pharma looks like it would require a completely different approach than anything that I do, and I was curious what styles and approaches different people  take to attack that sector successfully.   

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