BioMarin Pharmaceutical, Inc. (BMRN)

BioMarin has developed and commercialized three products in ten years, a remarkable accomplishment in the biopharmaceutical industry, and a testament to the company’s passion and dedication to patients with serious, unmet medical needs.
BioMarin has three approved products on the market today:
•Kuvan® (sapropterin dihydrochloride) Tablets for PKU
•Naglazyme® (galsulfase) for MPS VI
•Aldurazyme® (laronidase) for MPS I The year 2008 was a very important milestone in BioMarin’s history. We achieved our first profitable full year, with total revenues up 144 percent from 2007 to nearly $300 million, and increased sales across all of our three products. We continue to build an exciting pipeline, with a clinical portfolio featuring PEG-PAL for PKU and GALNS for MPS IVA, and a preclinical lineup that provides hope to many other patients with a variety of other rare diseases.
The year also brought with it the U.S. launch of Kuvan and we have been encouraged by the progress made thus far in a market with unique complexities. We continue to look for new ways to enhance our commercial efforts in this area and we remain very optimistic about the long-term potential of the product.
Other successes throughout the year included several regulatory achievements such as the approval of Naglazyme in Japan and South Korea, and the recent approval of Kuvan secured in the European Union by our partner Merck Serono.
In 2008, BioMarin achieved important milestones that will fuel future growth opportunities in the orphan drug industry. Today, as a fully integrated mid-cap biopharmaceutical company with three products on the market, strong revenues and cash reserves of nearly $560 million, we are confident and well positioned for the long-term. In 2009, we will continue to advance our pipeline and actively pursue valuable business development opportunities to bring increased value to patients, shareholders and employees. Logical buyout candidate In the BIOTECH field,should reward shareholders Into the future... TS

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