Proteostasis Therapeutics, Inc. (NASDAQ:PTI)

CAPS Rating: No stars

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Member Avatar Bigsef77 (70.32) Submitted: 3/13/2018 10:05:33 AM : Outperform Start Price: $4.81 PTI Score: -34.85

The FDA designates Proteostasis Therapeutics' (NYSE:PTI) PTI-428 a Breakthrough Therapy for the treatment of cystic fibrosis patients with two copies of the F508del genetic mutation who are currently on background therapy with Vertex Pharmaceuticals' (NASDAQ:VRTX) ORKAMBI (lumacaftor/ivacaftor).

Breakthrough Therapy status provides for more intensive guidance from the FDA on development, the involvement of more senior agency personnel and a rolling review of the marketing application.

PTI-428 is a CFTR amplifier in development as add-on therapy to approved CFTR modulators and as part of its triplet therapy (PTI-808, PTI-801, PTI-428).

Update: Shares are up 44% premarket on Tuesday, March 13, on light volume.

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ResearchLover

ResearchLover (73.73) Score: +157.48

Methylene blue, move aside!

Top
Pick
Member Name Member
Rating
Start
Date
Call Time
Frame
Start
Price
Stock
Gain
Index
Gain
Score Commentary
tmlax22 78.49 8/3/2016 Underperform 5Y $10.74 -71.93% +27.36% +99.29 0 Comment
zzlangerhans 99.58 12/12/2017 Underperform 1Y $5.55 -45.68% +3.01% +48.68 0 Comment
ababrmon 97.05 5/19/2017 Underperform 5Y $4.18 -27.87% +15.28% +43.15 0 Comment
Bigsef77 70.32 1/30/2018 3/13/2018 Outperform 1Y $4.81 -37.32% -2.47% -34.85 1 Comment
dianfra 93.37 3/26/2018 Outperform 5Y $4.94 -38.97% +4.74% -43.71 0 Comment
PayrollGeek 44.10 3/22/2018 Outperform 5Y $5.36 -43.75% +2.48% -46.23 0 Comment
portefeuille3 98.40 12/27/2017 Outperform 5Y $6.18 -51.21% +2.67% -53.89 0 Comment

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